Manabu Sasaki
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Affiliation | Occupational Therapy |
Position | Lecturer |
Executive | |
Degree | Master in Information Science |
E-mail address | msasaki@ (Add "yachts.ac.jp" to end) |
Researchmap(External Link) | https://researchmap.jp/manabu-sasaki?lang=en |
KAKEN(competitive funds, External Link) | |
Personal website(External Link) | |
Research Areas | My research focuses on understanding the causes of psychiatric disorders and reorganizing the treatment process based on new insights. Specifically, I employ a computational neuroscience approach. Many psychiatric conditions have seen dramatic advances in research in recent years. For example, while schizophrenia was once thought to stem from dopamine overproduction, a more recent integrative model suggests that it results from the interaction of genetic, neurodevelopmental, and environmental factors. Anatomical understanding of such disorders increasingly relies on models such as the cortico-thalamo-cortical loop or functional circuits that include the striatum and midbrain dopaminergic systems. In my work, I use mathematical models to simulate states associated with psychiatric disorders, recreating the anatomical structure of the cortex and subcortical regions. Until a few years ago, these simulations took weeks to compute, but now they can be completed in just a few days, expanding the scope of my research. It’s possible that such work could contribute to the development of new neuromodulation approaches. |
Research History | 1986 Department of Rehabilitation, Sapporo Yamanote Rehabili-Center 1988 Department of Rehabilitation, Sapporo Yamanoue Hospital 1991 Department of Physical Therapy, Medical Hospital, Hokkaido University 2000 Department of Occupational Therapy, Yamagata Prefectural University of Health Sciences |
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