石川 仁
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専門分野 | 公衆衛生学、疫学 |
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研究テーマ | 1.バイオマーカーの診断精度向上のための事前確率要因の検討 2.ワクチン接種率の地域間格差の要因研究 |
担当科目 | 学部:リハビリテーション概論、保健医療論、成人老年疾病論 I、小児疾病論、チーム医療論、ケアシステム論、卒業研究 大学院博士前期:特別研究 |
教育上の能力に関する事項 | 1.平成10年~平成17年 三重大学医学部・公衆衛生学講座・助教授 2.平成17年~平成20年 山形大学医学部・公衆衛生学講座・助教授 |
職務上の実績に関する事項 | 1.平成26年~平成29年 山形県村山総合支庁・医療監(兼)村山保健所長 2.平成29年~令和2年 山形県庄内総合支庁・医療監(兼)庄内保健所長 3.医師、社会医学系指導医・専門医、日本医師会認定産業医 |
主な研究業績 | |
2.A case of laboratory cross-contamination of Mycobacterium tuberculosis identified using comparative genomics.
3.Quantitative measurement of a candidate serum biomarker peptide derived from α2-HS-glycoprotein, and a preliminary trial of multidimensional peptide analysis in females with pregnancy-induced hypertension.
4.Simple quantitation for potential serum disease biomarker peptides, primarily identified by a peptidomics approach in the serum with hypertensive disorders of pregnancy.
5.Report of a case of acinic cell carcinoma of the upper lip and review of Japanese cases of acinic cell carcinoma of the minor salivary glands.
6.Postnatal epigenetic modification of glucocorticoid receptor gene in preterm infants: a prospective cohort study.
7.Effects of occupational environmental controls and work management on chromosomal damage in dental technicians in Japan.
8.Clinical peptidomic analysis by a one-step direct transfer technology: its potential utility for monitoring of pathophysiological status in female reproductive system disorders.
9.The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma.
10.Overexpression of TEX101, a potential novel cancer marker, in head and neck squamous cell carcinoma.
11.Postoperative prophylactic effect of fondaparinux for prevention of deep venous thrombosis after cemented total hip replacement: a comparative study.
12.Quantitative peptidomic analysis by a newly developed one-step direct transfer technology without depletion of major blood proteins: its potential utility for monitoring of pathophysiological status in pregnancy-induced hypertension.
13.Higher efficacy of urinary bone resorption marker measurements in assessing response to treatment for osteoporosis in postmenopausal women.
14.Different changes in resistance index between uterine artery and uterine radial artery during early pregnancy.
15.Relationship between decreased expression of squamous cell carcinoma antigen 2 and E-cadherin in primary cervical cancer lesions and lymph node metastasis.
16.Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate.
17.Irradiation prolongs survival of Alport mice.
18.Genotoxic effects of alcohol in human peripheral lymphocytes modulated by ADH1B and ALDH2 gene polymorphisms.
19.Reactivation of herpes simplex virus type 1 and varicella-zoster virus and therapeutic effects of combination therapy with prednisolone and valacyclovir in patients with Bell's palsy.
20.Aldo-keto reductase family 1, member B10 in uterine carcinomas: a potential risk factor of recurrence after surgical therapy in cervical cancer.
21.Gene-environmental interactions between alcohol-drinking behavior and ALDH2 and CYP2E1 polymorphisms and their impact on micronuclei frequency in human lymphocytes.
22.Relationship between fetal weight, placental growth and litter size in mice from mid- to late-gestation.
23.Genotoxic damage in female residents exposed to environmental air pollution in Shenyang city, China.
24.A polymorphism of the methionine synthase reductase gene increases chromosomal damage in peripheral lymphocytes in smokers.
25.Comparison between valsartan and valsartan plus cilnidipine in type II diabetics with normo- and microalbuminuria.
26.The effects of GSTM1 and GSTT1 polymorphisms on micronucleus frequencies in human lymphocytes in vivo.
27.Teratogenicity and developmental toxicity of chlorpyrifos. Maternal exposure during organogenesis in mice.
28.Differential regulation of apoptosis in the corpus luteum of pregnancy and newly formed corpus luteum after parturition in rats.
29.Evidence of association of the CYP2E1 genetic polymorphism with micronuclei frequency in human peripheral blood.
30.Effects of advanced maternal age on development of preimplantation mouse embryos obtained from delayed mating.
31. Analysis of teratogenic effects of maternal treatment with 2-bromopropane in mice. Ishikawa H, Yamauchi T.
32.Influence of gender, age and lifestyle factors on micronuclei frequency in healthy Japanese populations.
33.Effects of ALDH2 gene polymorphisms and alcohol-drinking behavior on micronuclei frequency in non-smokers.
34.Localization of GPI-80, a beta2-integrin-associated glycosylphosphatidyl-inositol anchored protein, on strongly CD14-positive human monocytes.
35.Micronucleus assay of human lymphocytes: a comparison of cytokinesis-block and human capillary blood lymphocytes methods.
36.Induction of micronuclei formation in preimplantation mouse embryos after maternal treatment with 2-bromopropane.
37.Analysis of cytogenetic and developmental effects on pre-implantation, mid-gestation and near-term mouse embryos after treatment with trichlorfon during zygote stage.
38.Developmental retardation of XO mouse embryos at mid-gestation.
39.Analysis of colchicine-induced chromosomal aberrations in embryos obtained from XO mice.
40.A 39,X/40,XY true hermaphrodite mouse with normal ovarian function.
41.Prolongation of duration of ovulation in ageing mice.
42.Cytogenetic effects of advanced maternal age and delayed fertilization on first-cleavage mouse embryos.
43.Neonatal mouse hip joint and hindlimb anomalies induced by prenatal exposure to Ara-C.
44.Carpal and tarsal bone development is highly sensitive to three antiproliferative teratogens in mice. Rahman ME, Ishikawa H, Watanabe Y, Endo A. Reprod Toxicol. 1996 10(6):485-9
45.Combined effects of maternal age and delayed fertilization on the frequency of chromosome anomalies in mice.
46.Viability, development and incidence of chromosome anomalies of preimplantation embryos from XO mice.
47.Stage specificity of Ara-C induced carpal and tarsal bone anomalies in mice.
48.The Timing of Appearance of Ossification Centers of Carpal and Tarsal Bones in Mouse Newborns.
49.Carpal and tarsal bone anomalies in mice induced by maternal treatment of Ara-C.
50.Decreased teratogen susceptibility in mouse fetuses obtained from delayed mating.
51.Ecological factors affecting body size of Japanese adolescents.
52.Compensatory development in preimplantation mouse embryos derived from delayed mating.
53.Growth and differentiation schedule of mouse embryos obtained from delayed matings.
和文(査読有り)
2.東日本大震災と深部静脈血栓症 - 40歳以上の女性避難者の危険因子の検討 -
3.地域住民における喫煙習慣と栄養素ならびに食品群摂取量との関連
4.生活習慣病予防における健康行動とソーシャルサポートの関連
和文(査読無し)
2.日本人高校生の体格と体型の年次推移
3. 0/100は安全か?
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