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前田 邦彦

氏名 前田 邦彦
所属・職位 理事長兼学長
学位 医学(博士)
E-Mail kumaeda@
(@以下にyachts.ac.jpを加えてください)
05maeda.jpg
専門分野 病理学,血液学,免疫学,組織学
研究テーマ ●樹状細胞の病理学的意義についての組織学的検討 ●リンパ濾胞における細胞相互作用の細胞・組織学的解析 ●網内系増殖症の臨床病理学的解析 ●山形県内における生活習慣病の地域特性に関する病理学的検討 ●山形県における悪性腫瘍の病理学的特性についての解析 ●悪性腫瘍の新しい治療(分子標的療法)についての調査・分析
担当科目  生体組織学,疾病科学,成人老年疾病論Ⅰ,成人老年疾病論Ⅱ,成人老年疾病論Ⅲ,チーム医療論,看護研究

教育上の能力

に関する事項

教育方法の実践 講義におけるバーチャル・スライドの活用
作成した教材等 「チーム医療論」において学習成果報告書を刊行

職務上の実績

に関する事項

厚生省死体解剖資格認定,日本病理学会認定病理専門医,日本臨床細胞学会認定細胞診専門医,日本リンパ網内系学会評議員,日本樹状細胞研究会世話人
主な研究業績

1) Kamio Y, Maeda K, Moriya T, Takasu N, Takeshita A, Hirai I, Kimura W, Yamakawa M.: Clinicopathological significance of cell cycle regulatory factors and differentiation- related factors in pancreatic neoplasms.  Pancreas 2010 Apr; 39(3): 345-352

 

2) Orii T, Takeda H, Kawata S, Maeda K, Yamakawa M: Differential immunophenotypic analysis of dendritic cell tumours. J Clin Pathol. 2010 Jun;63(6):497-503. Epub 2010 May 3.

 

3) Maeda K, Ninomiya Y, Matsuda M, Yamashita T:
Distribution, morphology and in situ phenotype of plasmacytoid dendritic cells in various human lymphoid tissues.  Int. Immunol 2010 22 (suppl): ii24,

 

4) Wada K, Maeda K, Tajima K, Kato T, Kobata T, Yamakawa M: Expression of BAFF-R and TACI in reactive lymphoid tissues and B-cell lymphomas. Histopathol 54(2): 221-232, 2009

 

5) Sanada S, Suzuki M, Shindo T, Suzuki S, Nakamichi T, Matsubara M, Maeda K.
Clinical and histological responses of renal amyloidosis to high-dose melphalan supported by autologous stem cell transplantation. Nephrol Dial Transplant. 2008 23(2):747-750.

 

6) Oka K, Nakamine H, Maeda K, Yamakawa M, Imai H, Tada K, Ito M, Watanabe Y, Suzuki H, Iwasa M, Tanaka I: Primary histiocytic sarcoma of the spleen associated with hemophagocytosis. Int J Hematol 87: 405-409, 2008

 

7) Takakubo Y, Takagi M, Maeda K, Tamaki Y, Sasaki A, Asano T, Fukushima S, Kiyoshige Y, Orui H, Ogino T, Yamakawa M: Distribution of Myeloid Dendritic Cells and Plasmacytoid Dendritic Cells in the Synovial Tissues of Rheumatoid Arthritis. J Rheumatol 35: 1919-1931, 2008

 

8)Watanabe T, Ebara S, Kimura S, Maeda K, Watanabe Y, Watanabe H, Kasai S, Nakano Y: Maternal vitamin B12 deficiency affects spermatogenesis at the embryonic and immature stages in rats. Development, Congenital Anomalies 47: 9-15, 2007

 

9) Kasajima-Akatsuka N, Maeda K: Development, Maturation and Subsequent Activation of Follicular Dendritic Cells (FDC) – Immunohistochemical Observation of Human Fetal and Adult Lymph Nodes –. Histochem Cell Biol 126: 261-273, 2006

 

10) Okazaki SI, Yamakawa M, Maeda K, Ohta N, Aoyagi M: Expression of glucocorticoid receptors in non-neoplastic lymphoid follicles and B cell type malignant lymphomas. J Clin Pathol 59: 410-416, 2006

 

11) Saitoh H-A, Maeda K, Yamakawa M: In situ observation of germinal center cell apoptosis during a secondary immune response. J Clin Exp Hematopathol 46: 73-82, 2006

 

12) Tsuge K, Takeda H, Kawada S, Maeda K, Yamakawa M: Characteriza

tion of dendritic cells in differentiated thyroid cancer.  J Pathol 205: 565 - 576, 2005

 

13) Maeda K, Takahashi T, Saitoh C, Watarai K, Wada K, Tajima K, Harada Y, Hiroshima Y, Yamakawa M: Interdifitating cell sarcoma – A report of an autopsy case and literature review -. J Clin Exp Hematopathol 45: 37-44, 2005

 

14) Moriya T, Kimura W, Semba S, Sakurai F, Hirai I, Ma J, Fuse A, Maeda K, Yamakawa M: Biological similarities and differences between pancreatic intraepithelial neoplasias and intraductal papillary mucinous neoplasms. Int J Gastrointest Cancer. 2005;35(2):111-1119

 

15) Maeda K, Takakubo Y, Ishida A, Yamakawa M: Distribution and characteristics of B-lymphocyte chemoattractant (BLC/ CXCL13) – expressing cells in the lymphoreticular tissues of various lymphoproliferative disorders. Lymphoreticular cells and Diseases. Proceedings of the 8th Japanese-Korean Lymphoreticular Workshop. Eds. Naito M, Park YE, pp 38, 2005 + CD-R0M

 

16) Kamo A, Araki Y, Maeda K, Watanabe H: Characteristics of invasive cells in the Zona Pelluecida durong follicular atresia in mice.  Zygote 12: 1 - 8, 2004

 

17) Tsuchiya D, Takamura H, Saito K, Kashiwa H, Maeda K, Yamashita H: Immunohistochemical diagnosis of a rare case of epithelioid malignant peripheral nerve sheath tumor with multiple metastases. Jpn J Ophthalmol 48: 565-569, 2004.

 

18) Shishido T, Nozaki N, Yamaguchi S, Shibata Y, Nitobe J, Miyamoto T, Takahashi H, Arimoto T, Maeda K, Yamakawa M, Takeuchi O, Akira S, Takeishi Y, Kubota I: Toll-like receptor-2 modulates ventricular remodeling after myocardial infarction. Circulation 108: 2905-2910, 2003.

 

19) Maeda K, Matsuda M, Suzuki H, Saitoh H: Immunohistochemical recognition of human follicular dendritic cells (FDCs) in routinely processed paraffin sections. J Histochem Cytochem 50: 1475-1485, 2002

 

20) Maeda K, Matsuda M, Yuda F, Saitoh H: Malignant lymphoma in Yamagata Prefecture: retrospective investigation on incidence and preferential sites, and a re-evaluation according to newly published WHO (World Health Organization) classification. J Clin Exp Hematopathol 42: 47-54, 2002

 

21) Kumazawa Y, Maeda K, Ito M, Yamakawa M, Hino T, Makamura C, Uchimura F, Arai S: Expression of glucocorticoid receptor nand 11b hydroxysteroid dehydrogenase in a case of pulmonary epithelioid hemangioendothelioma. J Clin Pathology: Mol Pathol 55: 61-64, 2002

 

22) Maeda K, Saitoh H, Liu D, Matsuda M, Yamakawa M: Development and maturation of follicular dendritic cells - Literature review and our preliminary observation - Dendritic Cells 11: 25 - 30, 2001

 

23) Mitsui H, Ito M, Maeda K, Semba S, Yamakawa M: Infiltrating dendritic cells in the bile duct lesions of primary biliary cirrhosis. Dendritic Cells 11: 39 - 41, 2001

 

24) Takamura H, Kanno M, Yamashita H, Maeda K: A case of orbital solitary fibrous tumor.  Jpn J Ophthalmol 45: 412-419, 2001

 

25) Nakamura N, Kuze T, Hashimoto Y, Hoshi S, Tominaga K, Sasaki Y, Shirakawa A, Maeda K, Abe M: Analysis of the immunoglobulin heavy chain gene of secondary diffuse large B-cell lymphoma that subsequently developed in four cases with B-cell chronic lymphocytic leukemia or lymphoplasmacytoid lymphoma (Richter syndrome). Pathol Int 50: 636-643, 2000

 

26) Tajima K, Maeda K, Fuyama S, Katagiri T, Kato T: Deposition of eosinophilic granule proteins in liver associated with allergic bronchopulmonary candidiasis. Digest Disease Sci 45: 1885 – 1888, 2000

 

27) Maeda K, Matsuda M, Suzuki H, Kasajima N, Liu D, Fuyama S, Arai S, Imai Y; A comparative study on immunohistochemical reactivity of the monoclonal antibodies recognizing human follicular dendritic cells (FDCs). - Immunophenotypical diversity of human FDCs-. Dendritic Cells 6: 43-49, 1996

 

28) Nagashima R, Maeda K, Imai Y, Takahashi T: Lamina propria macrophages in the human gastrointestinal mucosa: Their distribution, immunohistochemical phenotype, and function. J. Histochem. Cytochem. 44: 721-731, 1996

 

29) Sato H, Dobashi M, Maeda K: A change in then localization of the region trapping immune complexes in rat popliteal lymph nodes during development of germinal centers, with regard to the distribution of follicular dendnritic cells. Histol. Histopathol. 11: 293-302, 1996

 

30) Nagashima R, Takeda H, Maeda K, Ohno S, Takahashi T: Regression of duodenal mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori. Gastroenterology 111: 1674 - 1678, 1996

 

31) Kawanami T, Kato T, Daimaon M, Tominaga M, Sasaki H, Maeda K, Arai S, Shikama Y, Katagiri T: Hereditary caeruloplasmin deficiency: clinicopathological study of a patient.  J, Neurol. Neurosurg. Psychiatry 61: 506 - 509, 1996

 

32) Maeda K, Kosco-Vilbois MH, Burton GF, Szakal AK, Tew JG: Expression of the intercellular adhesion molecule-1 on high endothelial venules and on non-lymphoid antigen handling cells: interdigitating cells, antigen transporting cells and follicular dendritic cells. Cell Tissue Res 279: 47 - 54, 1995

 

33) Maeda K, Matsuda M,  Imai Y: Follicular dendritic cells: Structure as related to function.  Current Topics in Microbiology & Immunology 201: 119-139, 1995.

 

34) Maeda K, Matsuda M, Degawa N, Nagashima R, Fuyama S, Ito M, Arai S, Imai Y; In vitro immune complex binding assay to examine the mechanism of immune complex trapping by human follicular dendritic cells (FDC).   Adv. Exp. Med. Biol. 378: 317-319, 1995

 

35) Degawa N, Maeda K, Matsuda M, Nagashima R, Fuyama S, Ito M, Arai S, Imai Y; An immunohistochemical study on isotypes of the immune complexes trapped by follicular dendritic cells (FDC) in various human lymphoid tissues.  Adv. Exp. Med. Biol. 378: 281-283, 1995

 

36) Maeda K, Matsuda M, Nagashima R, Imai Y: A case report of unusual malignant lymphoma possibly derived from spleen.  Med. J. Kagoshima Univ. 47 (suppl.2): 147-154. 1995

 

37) Nagashima R, Maeda K, Matsuda M, Fuyama S, Imai Y: A case report of gastric tumor possibly of histiocytic origin. (True histiocytic lymphoma of stomach ?). Med. J. Kagoshima Univ. 47 (suppl.2): 103-106, 1995

 

38) Nagashima R, Maeda K, Degawa N, Dobashi M, Imai Y, Takahashi T: Distribution and phenotypes of macrophages in the gastrointestinal mucosa. Current topics in mucosal immunology 1993. edited by Tuchiya M, Yodoi J, Hibi T, and Miura S, Excepta Medica, Amsterdam, pp.233-236, 1994

 

39) Degawa N, Maeda K, Nagashima R, Matsuda M, Fuyama S, Arai S, Imai Y; Immunohistochemical analysis on tonsillar tissues of the patients with IgA nephropathy. I, Localization of IgA and related molecule.  Dendritic Cells 4: 101-111, 1994

 

40) Imai Y, Maeda K, Yamakawa M, Karbe Y, Matsuda M, Dobashi M, Sato H, Terashima K:   Heterogeneity and cellular origin of follicular dendritic cells. Adv. Exp. Med. Biol. 329: 339-344, 1993

 

41) Maeda K, Matsuda M, Narabayashi M, Nagashima R, Degawa N, Imai Y:  Follicular dendritic cells in malignant lymphomas - distribution, phenotypes and ultrastructures-.   Adv. Exp. Med. Biol. 329: 399-404, 1993

 

42) Maeda K, Matsuda M, Narabayashi M, Imai Y:  Follicular dendritic cell (FDC) in B-cell lymphoma - their distribution, morphology, phenotypes and functions-.  Dendritic Cells 2: 13-20, 1993

 

43) Yamakawa M, Maeda K, Imai Y: Characteristics of individual cell types in the omental milky spot. Yamagata Med. J. 11: 29-50, 1993

 

44) Maeda K, Burton GF, Padgett DA, Conrad DH, Huff TF, Masuda A, Szakal AK.  Tew JG:  Murine follicular dendritic cells and low affinity Fc-receptors for IgE (FceRII).   J Immunol 148, 2340-2347, 1992

 

45) Maeda K, Matsuda M, Imai Y, Szakal AK, Tew JG:  An immunohistochemical study of the phenotype of murine follicular dendritic cells (FDC).  Dendritic Cells 1,  23-30, 1992

 

46) Terashima K, Dobashi M, Maeda K, Imai Y:  Follicular dendritic cell and ICCOSOMES in germinal center reactions.   Seminars in Immunol 4, 267-274, 1992

 

47) Matsuda M, Yamakawa M, Fujita T, Maeda K, Imai Y:  Transformation of monocytes to interdigitating cells in vitro and in vivo. In: Lymphoreticular Cells - Fundamentals and Pathology -.  edited by Takahashi K and Sang-Ho K. Lymphoreticular Foundation, KumamotoJapan, pp.113-119,  1992

 

48) Maeda,K., Burton,G.F., Conrad,D.H., Huff,T.F., Szakal,A.K. and Tew,J.G.: Low affinity Fc-receptors for IgE and murine follicular dendritic cells (FDC). In Dendritic cells in lymphoid tissues. (eds.)  Imai,Y., Tew,J.G. and Hoefsmit E.C.M., Excerpta Medica, Amsterdam, pp.261-262, 1991

 

49) Burton,G.F., Maeda,K., Szakal,A.K. and Tew,J.G.: Immunogenecity of follicular dendritic cell (FDC) associated antigen.  in Dendritic cells in lymphoid tissues. (eds.)  Imai,Y., Tew,J.G. and Hoefsmit E.C.M., Excerpta Medica, Amsterdam, pp.149-158, 1991.

 

50) Imai,Y., Matsuda,M., Maeda,K., Yamakawa,M., Dobashi,M., Sato,H. and Terashima,K.: Dendritic cells in lymphoid tissues: their morphology, antigenic profiles and function.  in Dendritic cells in lymphoid tissues. (eds.)  Imai,Y., Tew,J.G. and Hoefsmit E.C.M., Excerpta Medica, Amsterdam, pp.3-14, 1991

 

51) Tew,J.G., Maeda,K., Imai,Y., Burton,G.F. and Szakal A.K.: What is a follicular dendritic cell ?  in Dendritic cells in lymphoid tissues. (eds.)  Imai,Y., Tew,J.G. and Hoefsmit E.C.M., Excerpta Medica, Amsterdam, pp.19-22, 1991

 

52) DiLosa,R.M., Maeda,K., Masuda,A., Szakal,A.K. and Tew,J.G.: Germinal center B cells and antibody production in the bone marrow.  J. Immunol., 146: 4071-4077, 1991

 

53) Terashima,K., Dobashi,M., Maeda,K. and Imai,Y.: Cellular components involved in the germinal center reaction. Res. Immunol., 142: 263-268, 1991

 

54) Imai Y, Matsuda M, Maeda K, Narabayashi M, Masunaga A:Follicular dendritic cells in lymphoid malignancies  -morphology, distribution and function-.  Lymphoid malignancy.  Immunocytology and cytogenetics. (ed.) M. Hanaoka, M.E. Kadin, A. Mikata, S. Watanabe,  Field & Wood, N.Y., 229-242, 1990